Younger: A Breakthrough Program To Reset Your Genes, Reverse Aging, and Turn Back the Clock 10 Years

Gynecologist Gottfried makes many promises to "reset your genes, reverse aging," etc., in this title. Some claims are correct, some not. Eating and sleeping right and staying mentally and physically active can boost well-being. But the author makes claims ranging far beyond the scientific literature. Regarding APOE4, a gene variant that when inherited from both parents can increase Alzheimer's risk, she states that using "the strategies in the Younger protocol, such as sticking to an anti-inflammatory diet, exercising, keeping blood sugar stable, and getting restorative sleep" will turn off the "bad variant." Nothing in the literature proves one can permanently "turn off" APOE4 with the above regiment. Likewise, discussing the BRCA1 and BRCA2 gene variants, which confer such a strong proclivity for breast cancer that many who test positive are advised to consider prophylactic mastectomies, the author writes breezily, "Turn off the breast cancer genes by eating more vegetables and less inflammatory meat, drinking less alcohol (no more than one serving twice per week), and keeping your inner clock ticking at a normal pace." We cannot permanently turn off those genes this way, according to current studies.